The 28-year-old Malawian import sustained the left knee injury when landing awkwardly during the third quarter of the Round 13 game against West Coast Fever on Saturday night.
“We are really disappointed for Mwai, who is obviously an integral part of our team, but also such a loved member of the Vixens family,” said head coach, Simone McKinnis.
“The support she has received so far from the players and Vixens support staff is a reflection of the person she is, and we will continue that support to ensure a successful rehabilitation program for as long as it takes.”